TORONTO METROPOLITAN UNIVERSITY

Course Outline (F2026)

BME772: Biomedical Signal Analysis

Instructor(s)Adam Lim [Coordinator]
Office: TBA
Phone: TBA
Email: adam.lim@torontomu.ca
Office Hours: Tuesday | 12pm - 1pm | Virtual
Calendar DescriptionThis is course will cover the different biomedical signals and the related signal modeling and analysis techniques. The topics covered in the course include an introduction to various physiological/biomedical signals such as the action potential, the electro-neurogram (ENG), the electromyogram (EMG), the electrocardiogram (ECG), the electroencephalogram (EEG), event-related potentials (ERPs), the electrogastrogram (EGG), the phonocardiogram (PCG), the carotid pulse (CP), signals from catheter-tip sensors, speech and oto-acoustic emission signals. The biomedical signal analysis portion of the course will deal with the analysis of concurrent, coupled and correlated processes, filtering for removal of artifact from biomedical signals, event detection techniques, analysis of wave-shape and waveform complexity associated with biomedical signals, mathematical modeling of biomedical systems, and medical decision support systems.
PrerequisitesBLG 601 and BME 632 and BLG 701 and BME 639
AntirequisitesELE 772
Corerequisites

None

Compulsory Text(s):
  1. Biomedical Signal Analysis, 3rd Edition, R.M. Rangayyan and S. Krishnan, IEEE Press Series in Biomedical Engineering, published by John Wiley and Sons Inc., 2024.
Reference Text(s):
  1. Biomedical Signal Analysis for Connected Healthcare, S. Krishnan, Elsevier, 2021.
  2. Technical articles and other relevant materials [to be posted if required]
Learning Objectives (Indicators)  

At the end of this course, the successful student will be able to:

  1. The students will be able to demonstrate their ability to apply different mathematical transforms and modeling techniques to physiological signals. (1c)
  2. The students will build the knowledge base needed for data acquisition, signal pre-processing, analysis, and interpretation of various real-world physiological signals. (1d)
  3. Solve design problems (4b)
  4. Analyse data to make decisions. (5b)
  5. Contribute to teamwork in an equitable and timely manner. (6a)
  6. Use Technical vocabulary related to Biomedical Engineering accurately. (7a)
  7. Make concise technical presentations to a peer group. (7b)
  8. Use graphics to analyse and display data. (7c)
  9. Understand how technological innovations can affect the well-being of those that use them. (8b)
  10. Gains a working knowledge of the literature of biomedical engineering and how it effects the day to day life (12b)

NOTE:Numbers in parentheses refer to the graduate attributes required by the Canadian Engineering Accreditation Board (CEAB).

Course Organization

3.0 hours of lecture per week for 13 weeks
2.0 hours of lab per week for 12 weeks
0.0 hours of tutorial per week for 12 weeks

Teaching AssistantsTBA
Course Evaluation
Theory
Midterm Exam 25 %
Final Exam 30 %
Laboratory
Lab Reports 25 %
Project 20 %
TOTAL:100 %

Note: In order for a student to pass a course, a minimum overall course mark of 50% must be obtained. In addition, for courses that have both "Theory and Laboratory" components, the student must pass the Laboratory and Theory portions separately by achieving a minimum of 50% in the combined Laboratory components and 50% in the combined Theory components. Please refer to the "Course Evaluation" section above for details on the Theory and Laboratory components (if applicable).


ExaminationsMidterm exam in Week 8, two hours (covers Weeks 1-7).
 
 Final exam, during exam period, three hours (covers Weeks 1-13).
Other Evaluation InformationCourse Project
 
 Project on state-of-the art biomedical analysis systems that may include implementation as well as a written report and presentation.  The details will be discussed in class. The project will have to be done in groups of three students. A report including the problem statement, methodology, and results for each must be submitted by the date which will be provided later.
 
 The report should be in IEEE double column format, and should not be more than 6 double-column, single-spaced pages (IEEE templates for Word and Latex may be downloaded from the IEEE website). The presentation of the report will also be required, and a presentation schedule will be provided later in the course.
Teaching MethodsIn-person lectures and labs
Other InformationNone

Course Content

Week

Hours

Chapters /
Section

Topic, description

1-2

4

Chapters 1 and 2

Biomedical signal analysis: Opportunities and Challenges. Nature of Biomedical Signals.
 


2-3

3

Chapter 3

Sources of noise, artifacts, and interferences in biomedical signals


3-5

8

Chapter 3

Filtering of biomedical signals


6-7

6

Chapters 4 and 5

Detection of events, waveshape analysis, and time-domain analysis


8

2

Midterm


8-10

6

Chapter 6

Frequency-domain analysis of biomedical signals


10-11

3

Chapter 7

Mathematical modeling of biomedical signals


11-12

4

Chapter 10

Machine learning applications
 
 Week 12: Project reports due


13

3

Review and project presentations


Laboratory(L)/Tutorials(T)/Activity(A) Schedule

Week

L/T/A

Description

2

Lab

Lab 0: Foundational aspects of biomedical signal analysis

3 and 4

Lab

Lab 1: Synchronized averaging

5 and 6

Lab

Lab 2: Filtering of the ECG for 60Hz removal

7 and 8

Lab

Lab 3: QRS Detection and ECG Rhythm Analysis

9 and 10

Lab

Lab 4: Frequency Domain Analysis

11 and 12

Lab

Open Lab for projects

University Policies & Important Information

Students are reminded that they are required to adhere to all relevant university policies found in their online course shell in D2L and/or on the Senate website

Refer to the Departmental FAQ page for furhter information on common questions.

Important Resources Available at Toronto Metropolitan University

Academic Program Advising Contacts

Visit the Electrical, Computer and, Biomedical Engineering department's faculty page for contact information.

Lab Safety

Students are to strictly adhere and follow:

  1. The Lab Safety information/guidelines posted in the respective labs,
  2. provided in their respective lab handouts, and
  3. instructions provided by the Teaching Assistants/Course instructors/Technical Staff.

During the lab sessions, to avoid tripping hazards, the area around the lab stations should not be surrounded by bags, backpacks etc, students should place their bags, backpacks etc against the walls of the labs and/or away from their lab stations in such a way that it avoids tripping hazards.

Accessibility

Please see the Toronto Metropolitan University's Accessibility website for the university's statement on accessibility.

Academic Accommodation Support

Academic Accommodation Support (AAS) is the university's accessibility services office, supporting students with disabilities. AAS works with students, faculty, and staff to create inclusive learning environments, reduce barriers, and promote accessibility across the university.

If you have (or suspect you may have) a disability, AAS can provide consultation, guide you through registration, develop accommodation plans where appropriate, and connect you with supports and services. For information about eligibility, documentation requirements, registration, deadlines, and available services, visit AAS.

Academic Accommodations (for students with disabilities) and Academic Consideration (for short-term extenuating circumstances) are governed by different university policies. Learn more about each process and how to access support. Students registered with AAS may request academic consideration (related or unrelated to their disability) if they experience extenuating circumstances that impact their ability to meet their shorter term academic obligations. This includes short term physical or mental health issues that are sudden/acute (e.g, the flu), unexpected illness or injury, hospitalization or treatment, and significant aggravation of a pre-existing condition. Please see Policy 167: Academic Consideration for more information and details.

Please note that there is no accommodation for missing/rescheduling or reweighting of tests - this is considered an alternate arrangement. Any student who misses a test/exam will be directed to submit an ACR to explore if possible alternate arrangements under Policy 167: Academic Consideration can apply .

Wellbeing Support

At Toronto Metropolitan University, we recognize that things can come up throughout the term that may interfere with a student’s ability to succeed in their coursework. These circumstances are outside of one’s control and can have a serious impact on physical and mental well-being. Seeking help can be a challenge, especially in those times of crisis.

If you are experiencing a mental health crisis, please call 911 and go to the nearest hospital emergency room. You can also access these outside resources at anytime:

If non-crisis support is needed, you can access these campus resources:

We encourage all Toronto Metropolitan University community members to access available resources to ensure support is reachable. You can find more resources available through the Toronto Metropolitan University Wellbeing Central website.